CitationWorkman, Megan; McDade, Thomas W.; Adair, Linda S.; & Kuzawa, Christopher W. (2015). Slow Early Growers Have More Muscle in Relation to Adult Activity: Evidence from Cebu, Philippines. European Journal of Clinical Nutrition, 69(12), 1350-1355.
AbstractBackground/Objectives: Adult skeletal muscle mass (SMM) protects against type 2 diabetes, but little is known about its developmental antecedents. We examined whether pace of early weight gain predicted adult SMM in a birth cohort from Cebu City, Philippines. In addition, we examined whether increases in SMM associated with adult muscle-building exercise varied according to the early growth. Subjects/Methods: Data came from 1472 participants of the Cebu Longitudinal Health and Nutrition Survey. Weight was measured at birth and at 6-month intervals through the age of 24 months. Adult SMM was estimated from anthropometric measurements when participants were 20–22-years old. Interviews provided the information on adult exercise/lifestyle habits. Results: SMM (mean±s.d.) was 20.8±3.9 kg (men) and 13.6±3.4 kg (women). Faster early weight gain predicted a higher adult SMM. After adjustment for height and lifestyle factors, strongest associations with SMM were found for 6–12 months growth in men (
Reference TypeJournal Article
Journal TitleEuropean Journal of Clinical Nutrition
McDade, Thomas W.
Adair, Linda S.
Kuzawa, Christopher W.