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Inflammatory Profiles in the Non-Pregnant State Predict Offspring Birth Weight at Cebu: Evidence for Inter-Generational Effects of Low Grade Inflammation – Cebu Longitudinal Health and Nutrition Survey

Inflammatory Profiles in the Non-Pregnant State Predict Offspring Birth Weight at Cebu: Evidence for Inter-Generational Effects of Low Grade Inflammation

Citation

Kuzawa, Christopher W.; Tallman, Paula Skye; Adair, Linda S.; Lee, Nanette R.; & McDade, Thomas W. (2012). Inflammatory Profiles in the Non-Pregnant State Predict Offspring Birth Weight at Cebu: Evidence for Inter-Generational Effects of Low Grade Inflammation. Annals of Human Biology, 39(4), 267-274. PMCID: PMC3532904

Abstract

Background: Although maternal infection and inflammation during pregnancy can adversely affect offspring birth weight (BW), whether low grade inflammation in the non-pregnant state predicts BW is unknown. Aim: To evaluate relationships between offspring BW and pro- and anti-inflammatory factors measured in parous but non-pregnant women. Subjects and methods: Data come from 234 parous Filipino females (21.5 ± 0.3 years) in the Cebu Longitudinal Health and Nutrition Survey, a population-based birth cohort in Metropolitan Cebu, Philippines. Pro-inflammatory [Interleukin-6 (IL-6), Interleukin-1 beta (IL-1

URL

http://dx.doi.org/10.3109/03014460.2012.692810

Reference Type

Journal Article

Year Published

2012

Journal Title

Annals of Human Biology

Author(s)

Kuzawa, Christopher W.
Tallman, Paula Skye
Adair, Linda S.
Lee, Nanette R.
McDade, Thomas W.

PMCID

PMC3532904